| ARCA Biopharma | www.arcabiopharma.com | Aurora | ARCA biopharma, Inc. is a biopharmaceutical company developing genetically-targeted therapies for heart failure and other cardiovascular diseases. The Company’s lead product is bucindolol, a next-generation beta-blocker and vasodilator with unique pharmacology, in development for heart failure and other indications. | Biotechnology |
| Avidity, LLC | www.avidity.com | Aurora | Avidity develops and sells molecular affinity tools for connecting molecules. Their patented AviTag™ technology employs a highly targeted enzymatic conjugation of a single biotin on a unique 15 amino acid peptide tag using the biotin ligase (BirA) from E. coli. Oriented on streptavidin-coated surfaces, this creates an ideal presentation for molecular binding interactions. | Biotechnology |
| Beacon Biotechnology | www.beaconbiotechnology.com | Aurora | Beacon Biotechnology’s BrightSPOT Reader detection platform and luciferase-based diagnostic assays combine cutting–edge hardware and novel biology in a way that is both powerful and simple. The BrightSPOT Reader will address new markets in home diagnostics, point-of-care diagnostics and bioterrorism that are limited by the shortcomings of existing technologies. The BrightSPOT Reader’s ability to diagnose disease at the doctor’s office will revolutionize the way medicine will be practice in the future. | Medical Device |
| BioAMPs International LLC | | Aurora | BioAMPS International, LLC is an emering pharmaceutical company focused on the development and commercialization of structurally-guided antimicrobial peptide solutions to the global problem of antibiotic resistance by gram-negative and gram-positive bacterial organisms. | Biotechnology |
| BioDesix | www.biodesix.com/ | Aurora | Biodesix, Inc. is a molecular diagnostics company advancing the revolution in personalized medicine by providing physicians timely and clinically useful information. The company has created ProTS™, a proprietary platform for the rapid and inexpensive discovery, validation, and commercialization of novel multiplexed protein diagnostics. Biodesix’s first product, VeriStrat®, is a simple blood test that provides oncologists guidance on the use of the appropriate therapy when treating lung cancer patients. | Biotechnology |
| BioNovo | www.bionovo.com | Aurora | Bionovo is a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, markets with significant unmet needs and billions in potential annual revenue. The company applies its expertise in the biology of menopause and cancer to design new drugs derived from botanical sources which have novel mechanisms of action. Based on the results of early and mid-stage clinical trials, Bionovo believes they have discovered new classes of drug candidates within their rich pipeline with the potential to be leaders in their markets. | Biotechnology |
| ClinImmune Labs | www.clinimmune.com | Aurora | ClinImmune Labs comprises five laboratories: - Histocompatibility - Clinical Immunology - Flow Cytometry - University of Colorado Cord Blood Bank - Human Stem Cell Processing facility These laboratories provide services to kidney, heart, lung, pancreas, and hematopoietic stem cell transplant programs around the world. | Biotechnology |
| ELISA Tech | www.elisatech.com | Aurora | ELISA Tech sells immunoassay products and couples this with a service to perform assays in a timely fashion. The goods supplied are immunoassay kits for cytokines, growth factors, and lipid inflammatory mediators. This company fills a niche in which it not only provides the assay kits but also performs the assays – and all for a lower cost than most commercial assay kits alone. All reagents and services are unconditionally guaranteed. ELISA Tech also specializes in making custom assays for compounds for which no commercial assays exist. It should be stressed that the samples assayed are for research only and none of the assays have any proven diagnostic value. | Biotechnology |
| Eurofins Medinet | www.eurofins-medinet.com | Aurora | Eurofins is a worldwide leader in its field of bioanalytical testing. With about $500 million annual sales and 5000 employees across 100 sites in 20 countries, Eurofins Scientific is a leading international group of laboratories providing an unparalleled range of testing and support services to the pharmaceutical, food, environmental and consumer products industries and to governments. The Group offers a portfolio of over 15,000 reliable analytical methods for characterizing the safety, identity, purity, composition, authenticity and origin of products and biological substances. Through research and development, in-licensing and acquisitions, the Group draws on the latest developments in the field of biotechnology and analytical sciences to offer its customers unique testing solutions. | Pharmaceutical |
| IHCtech | www.ihctech.net | Aurora | IHCtech offers a full line of custom quality animal and human tissue histopathology services from paraffin processing, embedding and sectioning, to plastic embedding of calcified bone and implanted tissues. Routine Hematoxylin and Eosin (H&E) staining as well as a large selection of special stains are offered. Specializing in Immunohistochemistry (IHC), we test antibodies, molecular probes, and biosensors in tissue or cells. We have a library of over 150 antibodies on hand we have validated. Let us process your tissue or cells with the care and expertise they deserve. | Pharmaceutical |
| Isogenis, Inc. | www.isogenis.com/ | Aurora | Isogenis is poised to become the provider of the most widely used and cost-effective immune modulating therapeutics that will revolutionize treatment of immune disorders, genetic diseases, and transplant tolerance. Isogenis' products will completely change the way transplantation is done today. These technologies stand to improve the quality of life of recipients, improve economic productivity, and significantly reduce the debilitating cost of health care.These products induce specific immune suppression, produce livelong acceptance of transplants, and are non-toxic. We base these products on the veto effect which occurs when specific T-cells programmed to destroy a transplant are all permanently inhibited. | Biotechnology |
| Lohocla Research Corporation | www.lohocla.com | Aurora | Uses genomic, proteomic, and gene array technology together with rational drug design to develop diagnostic and therapeutic products in the area of chronic pain, mental and addictive disorders. The company's proprietary gene, mRNA and protein diagnostic markers differentially ascertain depression, anxiety, manic depressive disorders and addictive disorders. | Biotechnology |
| MBC Pharma, Inc. | www.mikron.com | Aurora | MBC Pharma, Inc. is a biopharmaceutical company focused on discovering and developing drugs for bone diseases such as cancer and osteoporosis. MBC Pharma’s comprehensive and patented technology enables the highly efficient and specific delivery of drugs to bone. The approach has yielded promising lead structures in preclinical development for the treatment of multiple myeloma, metastatic bone disease caused by breast, prostate and lung cancer as well as osteoporosis and osteopenia. | Medical Device |
| PhosphoSolutions | www.phosphosolutions.com | Aurora | Designs and produces phosphoproteomic solutions using phosphor-specific antibodies. | Pharmaceutical |
| Proteome Resources | www.proteomeresources.com | Aurora | Manufactures and provides biochemistry tools and services or drug discovery and basic research. Supplies 98% pure ubiquitin enzymes, ubiquitin derivatives, ubiquitin-like proteins (UBLs), ubiquitin antibodies, custom protein and peptide services, and apoptosis tools. | Biotechnology |
| Qgenta | | Aurora | Harnessing innovative chemistry and biology in the development of molecular targeted agents for the treatment of cancer | Biotechnology |
| Sciona | www.sciona.com | Aurora | Sciona is a privately held, international company that provides personalized Health and Wellness recommendations based on an individual's diet, lifestyle and unique genetic profile (www.mycellf.com). Sciona was founded on a simple premise: to use the scientific information uncovered in the Human Genome Project for the benefit of consumers and consumer product companies. Sciona has built its business strategy around its patented application of evidence-based genetic information for the development of personalized products that help individuals optimize their health. Sciona is a world leader in Personal Genetics, using the science of genetics to personalize your nutrition and lifestyle choices to match your genes. | Biotechnology |
| SierraNeuro | www.sierraneuro.com | Aurora | of severe CNS diseases refractory to oral medications. Many currently available effective oral therapies can be highly toxic to body systems involved in the metabolism and excretion of these agents. This toxicity greatly limits a physician's ability to utilize agents that could otherwise be of great benefit. In addition, patients are often unable to consistently take oral medications because of their disease or related circumstances. Sierra has addressed these problems through a proprietary development process that reformulates highly effective but systemically toxic oral medications, enabling placement into an implantable drug delivery pump for direct administration in the fluid around the brain. This innovative delivery approach will expand treatment options in refractory CNS diseases including Epilepsy, Schizophrenia, Bipolar Disorder, Anxiety Disorders and Major Depression. | Biotechnology |
| Taiga Biotechnologies | www.taigabiotech.com | Aurora | Taiga Biotechnologies was founded to develop novel approaches to treat hematological diseases, including cancers, immunodeficiencies and autoimmune conditions. Our three-pronged approach combines novel breakthroughs in cellular, biologic and small molecule approaches to treat and manage these diseases. | Biotechnology |
| Taligen Therapeutics | www.taligentherapeutics.com | Aurora | Taligen Therapeutics is focused on the discovery and development of novel protein therapeutics that modulate the alternative pathway of the complement system to treat a wide range of inflammatory conditions and diseases. The company's lead therapeutic candidates are monoclonal antibodies and recombinant fusion proteins that target key factors in the alternative pathway, which Taligen's founders have validated as an important amplification loop in the inflammation process. | Biotechnology |
| Technology Transfer Office - UC-Denver | | Aurora | The Technology Transfer Office provides services to the UC Denver Research and Inventor Community. The TTO works with researchers and inventors at various stages during the research and technology transfer process. The TTO helps researchers with arrangements to access and share proprietary information and research materials, and to define IP terms and conditions in sponsored research agreements and consulting agreements. After an invention has been conceived, TTO works with inventors to: clarify the invention disclosure and identify the IP; ascertain if the IP is protectable and commercially viable; engage and assist external legal counsel to prepare the patent application and prosecute it; and contact and pursue innovative adopter companies and entrepreneurs to license the IP for further development, commercialization, and public use. | Biotechnology |
| Tissue Genetics, Inc. | www.tissuegenetics.com/ | Aurora | Tissue Genetics is a medical diagnostic test company specializing in the development of tissue-based tests for inherited genetic diseases. The company offers a clear alternative to present inflexible and overly complex diagnostic approaches by providing a simple, efficient two-pronged strategy for diagnosing genetic diseases in patients. A single platform technology will be used to develop individualized genetic tests for a number of common genetic diseases, beginning with the genetic cancers. | Biotechnology |
| Touch of Life Technologies | www.toltech.net/ | Aurora | The human body is complex and beautiful. Artists through the ages have studied the human body in detail and healers have dissected and catalogued it. In 1993 scientists at the University of Colorado created the Visible Human by milling away millimeter slices of a cadaver and photographing the remaining block, thereby digitizing the anatomy. In this way they took the fascination we have for our own anatomy and brought it into the information age. Touch of Life Technologies (ToLTech) is the sole licensee of these innovations and is creating products that will allow students, practitioners and the public in general to better see, feel, and understand the beauty and complexity of the human body. | Biotechnology |
| ValveXchange, Inc. | www.valvexchange.com | Aurora | ValveXchange Inc. ("VXi") is a medical device company dedicated to improving the lives of patients requiring heart valve replacements. VXi holds patented technology on a two-piece bioprosthetic tissue valve that resolves the long standing compromises between conventional mechanical and tissue heart valves. The VXi technology is being designed to be easily adopted by surgeons and provide optimal patient benefits. | Medical Device |
| Western States Biopharma | | Aurora | Western States is a privately held biopharmaceutical company developing novel therapies that selectively modulate adaptive immunity and treat inflammatory diseases. Currently valued over $18B, the global autoimmune market still does not have therapies that adequately address either the efficacy or safety needs of the target populations , The company founders have deep experience in discovering, developing, and commercializing therapies in autoimmune disease and plan to utilize both small molecule and biologic approaches. Western States has several exploratory programs based on technology from the University of Colorado Denver, Anschutz Medical Center. | Biotechnology |
| Work, Education and Lifelong Learning Simulation (WELLS) Center | www.wellssimulationcenter.org | Aurora | The WELLS Center is taking clinical education in Colorado to a new level. For the first time in Colorado, one facility offers a complete array of state-of-the-art patient simulation tools for building clinical knowledge. Even more exciting, high-speed datacasting technology makes this unique resource available remotely. Students, faculty and practicing nurses and physicians from throughout Colorado can enhance their diagnostic and clinical skills at the WELLS Center either on-site or on-line. Housed in the new Bioscience East building at Fitzsimons, the WELLS Center represents a unique collaboration among educators, providers and policymakers. | Biotechnology |